A mountain-top view of Tbilisi; the Republic of Georgia's ancient and fascinating capital

A mountain-top view of Tbilisi; Georgia's ancient and fascinating capital

The Fight Against Drug-Resistant "Superbugs" Starts Here

Welcome to the new frontier in the fight against bacterial disease - a frontier defined by technology that is nearly one century old, but which remains new to Western science. "Phage therapy" - a technology that employs "good viruses" called bacteriophages (commonly known as "phages") to destroy infection-causing bacteria, has been used safely and successfully for more than ninety years to treat and prevent a wide array of illnesses in the former Soviet Union. Capable of application in liquid, tablet, or powder form, phages obliterate the specific bacterial strains which nature designed them to attack, while remaining harmless to the surrounding environment.

The Growing Threat of Antibiotic Resistance

A 2014 World Health Organization report concluded that the emergence of antibiotic-resistant "superbugs" threatens to become a worse global health crisis than the AIDS epidemic. In his Foreword to this report, the World Health Organization's Assistant Director-General for Health Security, Dr. Keiji Fukuda, warned that this development constitutes "a problem so serious that it threatens the achievements of modern medicine;" adding that “[a] post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century." 1 The Review on Antimicrobial Resistance commissioned by United Kingdom Prime Minister David Cameron issued a paper in December 2014 which estimated that "[a]ntimicrobial-resistant infections currently claim at least 50,000 lives each year across Europe and the US alone, with many hundreds of thousands more dying in other areas of the world," while projecting that the number of annual deaths attributable to antimicrobial resistance could climb to 10 million by 2050. The Review further suggests that antimicrobial resistance could further trigger a reduction of 2% to 3.5% in Gross Domestic Product (GDP) . . . cost[ing] the world up to 100 trillion USD" by 20502

Notwithstanding the gravity of the threat, the global pharmaceutical industry has not responded with new antibiotic drugs. Quite to the contrary, Britain's Royal Pharmaceutical Society reports that "no new class of antibiotics has been discovered since 1987, largely because the financial returns for finding new classes of antibiotics are too low."3 Moreover, concerns continue to multiply regarding the health effects of antibiotic use. Scientists have observed that "even when effective antibiotics are available, it is becoming increasingly apparent that broad-spectrum antibiotics can have sustained and detrimental effects on the body's communities of beneficial bacteria . . . which, according to a growing body of research, play a vital role in human nutrition."4

Much of the "Mainstream" Media Remains Unaware or Ill-Informed Regarding Phage Therapy

Clearly, the age when antibiotics offered an all-purpose, "magic bullet" cure for bacterial infections has ended. Yet, the mainstream global media seems completely unaware that any other alternative exists. Reacting to the World Health Organization's 2014 report, The New York Times editorialized that [t]he most urgent need is to minimize the overuse of antibiotics in medicine and agriculture, which accelerates the development of resistant strains," and that "[t]he pharmaceutical industry needs to be encouraged to develop new antibiotics to supplement those that are losing their effectiveness."1 Meanwhile, some online resources exist which correctly highlight the risks of continued antibiotic use - but which suggest that the only remedy is to reduce our reliance upon these drugs. In other words, a parent with an ill child should reject a doctor's prescription for antibiotics and “wait a few days to see if the problem resolves on its own."2

Western Science Rediscovers the Potential of Phage Therapy

Some Western scientists have begun to recognize the potential of phage therapy as a timely and viable alternative. Indeed, University of Miami biology professor Eric C. Keen has written that "[t]oday, a century after their discovery, phages are poised to fulfill their early promise and make a significant contribution to the treatment of bacterial disease."1 Professor Keen predicts that over the "next 100 years of phage research . . . [a] variety of phage-based therapies will become widely used in medicine and agriculture, especially in the context of drug-resistant and/or long-term bacterial infections."2 Yet, even Professor Keen's upbeat assessment omits one essential fact: while the West relied exclusively upon antibiotics, scientists in the former Soviet Republic of Georgia perfected phage therapy - transforming a theory into commercially available products which treat a wide variety of bacterial infections. Perhaps most significantly, these products can effectively remediate Methicillin-resistant Staphylococcus aureus (MRSA) and other potentially deadly bacterial pathogens like Escherichia coli (E.coli). In short, phage therapy no longer remains a research project, but has become a safe and effective weapon against antibiotic-resistant "superbugs.”

Phage Therapy: Safe, Reliable, and Commercially Viable

Unlike antibiotics, phages do not destroy "good bacteria." Moreover, phages do not cause debilitating side effects in human beings such as severe stomach upset, nerve damage, and blood abnormalities. Properly dosed multi-phage preparations called "phage cocktails" have proven effective in remediating dangerous infections like MRSA and e-coli poisoning, which have otherwise shown significant resistance to antibiotics. Moreover, as set forth in more detail in the section of this site entitled "Safe and 100% Natural," phage therapy possesses and outstanding safety record in Georgia and throughout the former Soviet Union.

Particularly due to its versatility in both the preventative and remediation stages of the fight against bacteriological threats, phage therapy has caught the attention of commercial, educational, and government entities on five continents. ABTI is uniquely positioned to transform this interest into a viable commercial enterprise. Based in the Republic of Georgia (universally regarded as phage therapy's "Global Center of Excellence"), ABTI possesses a deep and abiding connection to the scientific expertise which has preserved and perfected phage therapy for almost one century.